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   This is an informational page, providing you information about the Genetic and Hereditary diseases in Shetland Sheepdogs  that we test and guarantee against in our dogs here at L&M SHELTIES . 


  Below  is the list of Diseases (Genetic or Hereditary) and Health issue(s) in Shelties; due to copyright laws I am providing a link to the various web sites with the information on each. 

vWD3 (click here)

von Willebrands Disease III

Von Willebrand's disease vWD, an inherited bleeding disorder.


DM(click here)

Degenerative Myelopathy

Degenerative myelopathy (DM) is a slowly progressive spinal cord disorder that resembles Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig’s Disease) in people. The inevitable result for dogs with DM is paraplegia—hind end paralysis.

DMS (click here) 


Dermatomyositis (DMS)* is an autoimmune disease of the skin and muscle that occurs in both humans and dogs.

CNGA1-PRA (click here)        CNGA1-PRA testing(clickhere) 

Sheltie Progressive Retinal Atrophy

Progressive retinal atrophy is a group of genetic diseases seen in certain breeds of dogs and, more rarely, cats. Similar to retinitis pigmentosa in humans, it is characterized by the bilateral degeneration of the retina, causing progressive vision loss culminating in blindness. The condition in nearly all breeds is inherited as an autosomal recessive trait, with the exception of the Siberian Husky and the Bullmastiff. There is no treatment.

CEA(click here)

Collie Eye Anomaly

Collie eye anomaly is a congenital, inherited, bilateral eye disease of dogs, which affects the retina, choroid, and sclera. It can be a mild disease or cause blindness. CEA is caused by a simple autosomal recessive gene defect. There is no treatment.

MDR1(click here)

Multi-Drug Resistance Gene

Multi-Drug Resistance Gene (MDR) codes for a protein that is responsible for protecting the brain by transporting potentially harmful chemicals away.

Corneal Dystrophy(click here)

Corneal Dystropy

Corneal dystrophy is a non-inflammatory opacification (clouding) of the cornea (the clear outer surface of the eye). Depending on the degree to which the cornea is affected, blindness may result, as both eyes are always involved.

CHD(click here)

Canine Hip Dysplasia

Hip dysplasia is an inherited condition resulting from an improperly formed hip joint.

Hypothyroidism(click here)

Hypothyroidism, also called underactive thyroid disease, with hypothyroidism, your thyroid gland does not make enough thyroid hormone.

Genetic Diseases and Heath Issues

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